Psoriasis is characterized by well-demarcated erythematous plaques with a white or silver scale, primarily on the extensor surfaces (e.g. knees, elbows); Auspitz sign is the appearance of pinpoint bleeding when scales are scraped off.
Associated with drugs (e.g. beta-blocker, NSAIDS, ACE inhibitor, oral steroids, tetracycline); Therefore, do not give systemic steroids for psoriasis as systemic steroids worsen psoriasis.
Management:-
1. Topical high-potency steroids; Topical vitamin D analogues (e.g. calcipotriene), topical retinoids are used to get the patient off steroids.
2. Coal tar preparation.
3. Topical calcineurin inhibitors (e.g. pimecrolimus, tacrolimus).
4. Antitumor necrosis factor (TNF) inhibitors (e.g. etanercept, adalimumab, infliximab),
methotrexate, cyclosporine and Phototherapy (e.g. PUVA) for severe extensive disease.
Test for tuberculosis with PPD before starting anti-TNF-ɑ inhibitors.
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